Fields of Interest

Kristiina Aalto-Korte

• Occupational dermatology, especially allergic contact dermatitis: isocyanates, acrylates, antimicrobials, allergens in PVC gloves

1. Suuronen K, Pesonen M, Aalto-Korte K. Occupational contact allergy to
   cocamidopropyl betaine and its impurities.
   Contact Dermatitis. 2012 Feb 24. doi: 10.1111/j.1600-0536.2011.02036.x. [Epub ahead of print] PubMed PMID: 22364510.
   
   
2. Aalto-Korte K, Pesonen M, Kuuliala O, Alanko K, Jolanki R. Contact allergy to aliphatic polyisocyanates based on hexamethylene-1,6-diisocyanate (HDI).
   Contact Dermatitis. 2010 Dec;63(6):357-63.
   
   
3. Mälkönen T, Alanko K, Jolanki R, Luukkonen R, Aalto-Korte K, Lauerma A,
   Susitaival P. Long-term follow-up study of occupational hand eczema.
   Br J
   Dermatol. 2010 Nov;163(5):999-1006.
   
   
4. Aalto-Korte K, Henriks-Eckerman ML, Kuuliala O, Jolanki R. Occupational
   methacrylate and acrylate allergy--cross-reactions and possible screening
   allergens.
   Contact Dermatitis. 2010 Dec;63(6):301-12.
   
   
5. Contact Dermatitis. 2009 Jul;61(1):9-21.
   
   
6. Helaskoski E, Kuuliala O, Aalto-Korte K. Occupational contact urticaria caused by cyclic acid anhydrides.
   Contact Dermatitis. 2009 Apr;60(4):214-21.
   
   
7. Aalto-Korte K, Kuuliala O, Suuronen K, Alanko K. Occupational contact allergy to formaldehyde and formaldehyde releasers.
   Contact Dermatitis. 2008 Nov;59(5):280-9.
   
   
8. Aalto-Korte K, Alanko K, Kuuliala O, Jolanki R. Occupational methacrylate and acrylate allergy from glues. Contact Dermatitis. 2008 Jun;58(6):340-6.
   
9. Aalto-Korte K, Ackermann L, Henriks-Eckerman ML, Välimaa J, Reinikka-Railo H, Leppänen E, Jolanki R. 1,2-benzisothiazolin-3-one in disposable polyvinyl chloride gloves for medical use.
   Contact Dermatitis. 2007 Dec;57(6):365-70.
   
   
10. Aalto-Korte K, Alanko K, Kuuliala O, Jolanki R. Methacrylate and acrylate allergy in dental personnel.
    Contact Dermatitis. 2007 Nov;57(5):324-30.

[ top ]

Dr. Tove Agner

• Irritant contact dermatitis
  
• Combined effect of irritants and allergens
  
• Bioengineering methods
  
• Occupational hand eczema – risk factors and prognosis
  
• Hand eczema – twin studies – incidence and prognosis
  
• Information and compliance in relation to allergic contact dermatitis
  
• Atopic dermatitis – birth cohort study
  

[ top ]

Prof. Klaus E. Andersen

• Botanical dermatology - Compositae
  
• Follow up on the TOACS cohort (The Odense Adolescence Cohort Study)
  
• Follow up on the DARC cohort (Danish Allergy Research Centre)
  
• Nanotechnology and allergy, Clinical contact dermatitis, Development of an experimental human contact dermatitis model, Dermatotoxicology, Patch test technique

1. Kristian F. Mose, Klaus E. Andersen and Lars Porskjær Christensen. Stability of selected volatile contact allergens in different patch test chambers under different storage conditions.
   Contact Dermatitis 2012;66:172-179.
   
   
2. Pallesen, Kristine A ; Robinson, Sian; Toft, Palle; Andersen, Klaus Ejner . Successful Treatment of Toxic Epidermal Necrolysis/Stevens-Johnson Syndrome Overlap with Human Granulocyte Colony Stimulating Factor: A Case Report.
   Acta Dermato Venereologica, 2012: 92, 212-213
   
   
3. Madsen JT, Andersen KE. Allergic contact dermatitis caused by the emulsifier triceteareth-4-phosphate.
   Contact Dermatitis. 2012; 66:159-60
   
   
4. Clemmensen, A; Andersen, F ; Petersen, T K ; Hagberg, Oskar ; Andersen, Klaus Ejner . Applicability of an exaggerated forearm wash test for efficacy testing of two corticosteroids, tacrolimus and glycerol, in topical formulations against skin irritation induced by two different irritants.
   Skin Research and Technology , 2011; 17, 56-62.
   
   
5. Madsen, Jakob Torp; Vogel, Stefan ; Johansen, Jeanne Duus ; Sørensen, Jens Ahm; Andersen, Klaus Ejner; Nielsen, Jesper Bo . Percutaneous penetration characteristics and release kinetics of contact allergens encapsulated in ethosomes.
   Cutaneous and Ocular Toxicology , 2011; 30,:38-44.
   
   
6. Carøe, Caroline ; Andersen, Klaus Ejner; Mørtz, Charlotte G . Fluctuations in the prevalence of nickel and cobalt allergy in eczema patients patch tested after implementation of the nickel regulation in Denmark.
   Contact Dermatitis 2011; 64,:126-31.
   
   
7. Paulsen, Evy; Andersen, Klaus Ejner . Screening for Compositae sensitization with pure allergens: implications of molecular structure, strength of reaction, and time of testing.
   Contact Dermatitis 2011; 64,: 96-103.
   
   
8. Farage MA, Maibach HI, Andersen KE, Lachapelle JM, Kern P, Ryan C, Ely J, Kanti A. Historical perspective on the use of visual grading scales in evaluating skin irritation and sensitization.
   Contact Dermatitis. 2011;65:65-75.
   
   
9. Carøe C, Andersen KE, Thyssen JP, Mortz CG. Fluctuations in the prevalence of chromate allergy in Denmark and exposure to chrome-tanned leather.
   Contact Dermatitis. 2010 ;63:340-6.
   
   
10. Mortz CG, Andersen KE. Fragrance mix I patch test reactions in 5006 consecutive dermatitis patients tested simultaneously with TRUE Test® and Trolab® test material. Contact Dermatitis. 2010;63:248-53
    

[ top ]

Andreas Bircher

[ top ]

Prof. Magnus Bruze

• Corticosteroids (Co 1)
  
• Epoxy resins (Co 2)
  
• Gold *
  
• Nickel (Co 3)
  
• Perfume **
  
• Phenol-formaldehyde resins (Co 4)
  
• Preservatives (Co 5)
  
• Isocyanates ***
  

1. Isaksson M, Bruze M, Lepoittevin JP, Goossens A.
   Patch testing with serial dilutions of budesonide, its R and S diastereomers, and potentially cross-reacting substances.
   Am J Contact Dermat 2001; 12(3):170-176.
   Abstract
   
2. Isaksson M, Bruze M.
   Repetitive usage testing with budesonide in experimental nickel--allergic contact dermatitis in individuals hypersensitive to budesonide.
   Br J Dermatol 2001; 145(1):38-44.
   Abstract
   
3. Nilsson AM, Gafvert E, Salvador L, Luthman K, Bruze M, Gruvberger B et al.
   Mechanism of the antigen formation of carvone and related alpha, beta-unsaturated ketones.
   Contact Dermatitis 2001; 44(6):347-356.
   Abstract
   
4. Hindsen M, Bruze M, Christensen OB.
   Flare-up reactions after oral challenge with nickel in relation to challenge dose and intensity and time of previous patch test reactions.
   J Am Acad Dermatol 2001; 44(4):616-623.
   Abstract
   
5. Ponten A, Bruze M.
   Contact allergy to epoxy resin based on diglycidyl ether of bisphenol F.
   Contact Dermatitis 2001; 44(2):98-99.
   Abstract
   

[ top ]

Prof. Thomas L. Diepgen

• ATOPIC DERMATITIS and atopy:
  natural history of AD; prognostic factors; subgroups; autoallergy; epidemiology; evaluation of eczema schools for AD (funded by German Health Ministry)
  
• OCCUPATIONAL CONTACT DERMATITIS
  register study of OCD in North Bavaria and Saarland; prospective AUDI cohort study; secondary prevention program in health care workers, rehabilitation of OCD; prospective cohort study in hairdressers and nurses; costs of OCD
  
• REGULATION (occupational skin diseases, allergens, irritants)
  
• SUN-ALLERGY (EU project)
  
• EVIDENCE BASED DERMATOLOGY (Cochrane Skin Group, antihistamines in AD)
  
• DERMATOLOGY & INTERNET
  Dermatology Online Atlas, CD-ROM, e-Health: MedCertain (EU-project), Internet-based health education & prevention for AD, skin cancer
  
• OTHERS
  Efficacy of barrier creams (using bio-engineering methods)
  Skin cancer prevention: screening programmes in companies
  Prevalence of skin diseases in Europe (cooperation with EDEN, EDF)
  

1. Diepgen TL, Coenraads PJ (1999)
   The epidemiology of occupational contact dermatitis.
   Int Arch Occup Environ Health 72: 496-506
   Abstract
   
2. Diepgen TL, Coenraads PJ (2000)
   The impact of sensitivity, specificity and positive predictive value of patch testing: The more you test, the more you get?
   Contact Dermatitis 42:315?7
   Abstract
   
3. Mahler V, Diepgen TL, Kuss O, Leakakos T, Truscott W, Schuler G, Kraft D, Valenta R (2000)
   Mutual boosting effects of sensitization with timothy grass pollen and latex glove extract on IgE antibody responses in a mouse model.
   J Invest Dermatol. 114(5):1039?43
   Abstract
   
4. Schnetz E, Diepgen TL, Elsner P, Frosch PJ, Klotz AJ, Kresken J, Kuss O, Merk H, Schwanitz HJ, Wigger?Alberti W, Fartasch M (2000)
   Multicentre study for the development of an in vivo model to evaluate the influence of topical formulations on irritation.
   Contact Dermatitis 42: 336?43
   Abstract
   
5. Funke U, Fartasch M, Diepgen TL (2001)
   Incidence of work related hand eczema in apprenticeship - first results of a prospective cohort study in the car industry.
   Contact Dermatitis 44:166-172
   Abstract
   
6. Dickel H, Kuss O, Blesius CR, Schmidt A, Diepgen TL (2001)
   Report from the register of occupational skin diseases in Nothern Bavaria (BKH-N).
   Contact Dermatitis 44: 258-9
   Abstract
   
7. Dickel H, Kuss O, Blesius CR, Schmidt A, Diepgen TL (2001)
   Occupational skin diseases in Nothern Bavaria between 1990 and 1999: a population based study.
   Br J Dermatol 145(3): 453-462
   Abstract
   
8. Diepgen TL (2001)
   Atopic Dermatitis - The Role of Social Factors.
   J Am Acad Dermatol. 45: S44-8
   Abstract
   
9. Eysenbach G, Diepgen TL (2001)
   The role of e-health and consumer health informatics for evidence-based patient choice.
   Clinics in Dermatology 19: 11-17
   Abstract
   

[ top ]

Jeanne Duus Johansen

• Perfume allergy
  
• Contact allergy to hair dyes
  
• Contact allergy to preservatives
  
• Contact allergy to chromium
  
• Combination effects: irritants/allergens
  
• Airway symptoms related to perfume exposure
  
• Risk assessment model for elicitation of contact allergy
  
• Threshold of reaction to systemic nickel exposure
  
• Disease patterns related to contact allergy
  
• Surveillance systems for contact allergy
  
• Occupational contact dermatitis
  
• Eczema prognosis
  

[ top ]

Catherina Foti

• Allergic contact dermatitis
  
• Food allergens
  
• Cosmetics
  
• Urticaria
  
• Photoallergic contact dermatitis

1. Kerr AC, Ferguson J, Haylett AK, Rhodes LE, Adamski H, Alomar A, Serra E,
   Antoniou C, Aubin F, Vigan M, Biedermann T, Fischer J, Bourrain JL, Bruynzeel D,
   Rustemeyer T, Carrascosa JM, Chowdhury MM, de la Cuadra J, Foti C, Gardeazabal J,
   Gawkrodger DJ, Gimenez-Arnau A, Goncalo M, Goossens A, Lecha M, Marguery MC,
   Neumann NJ, Niklasson B, Peyron JL, Pigatto P, Spiewak R, Stone N, Tanew A,
   Thomas P, Bonnevalle A, Wilkinson SM, Wolf P, Gruber-Wackernagel A, Wulf HC. A
   European Multi-centre Photopatch Test Study (EMCPPTS). Br J Dermatol. 2012 Jan [Epub ahead of print]
   
   
2. Foti C, Damiani E, Zambonin CG, Cassano N, Nettis E, Ferrannini A, Calvano CD,
   Aresta A, Romita P, Aloia AM, Vena GA. Urticaria and angioedema to rubisco
   allergen in spinach and tomato. Ann Allergy Asthma Immunol. 2012 Jan;108(1):60-1
   
   
3. Ballini A, Cantore S, Fatone L, Montenegro V, De Vito D, Pettini F, Crincoli
   V, Antelmi A, Romita P, Rapone B, Miniello G, Perillo L, Grassi FR, Foti C.
   Transmission of nonviral sexually transmitted infections and oral sex. J Sex Med.
   2012 Feb;9(2):372-84
   
   
4. Foti C, Cassano N, Vena GA, Angelini G. Photodermatitis caused by oral
   ketoprofen: two case reports. Contact Dermatitis. 2011 Mar;64(3):181-3
   
   
5. Stingeni L, Foti C, Cassano N, Bonamonte D, Vonella M, Vena GA, Angelini G,
   Lisi P. Photocontact allergy to arylpropionic acid non-steroidal
   anti-inflammatory drugs in patients sensitized to fragrance mix I. Contact
   Dermatitis. 2010 Aug;63(2):108-10
   
   
6. Bonamonte D, Foti C, Lionetti N, Rigano L, Angelini G. Photoallergic contact
   dermatitis to 8-methoxypsoralen in Ficus carica. Contact Dermatitis. 2010
   Jun;62(6):343-8
   
   
7. Foti C, Bonamonte D, Cassano N, Vena GA, Angelini G. Photoallergic contact
   dermatitis. G Ital Dermatol Venereol. 2009 Oct;144(5):515-25
   
   
8. Foti C, Zambonin CG, Cassano N, Aresta A, Damascelli A, Ferrara F, Vena GA.
   Occupational allergic contact dermatitis associated with dimethyl fumarate in
   clothing. Contact Dermatitis. 2009 Aug;61(2):122-4
   
   
9. Foti C, Bonamonte D, Conserva A, Stingeni L, Lisi P, Lionetti N, Rigano L,
   Angelini G. Allergic and photoallergic contact dermatitis from ketoprofen:
   evaluation of cross-reactivities by a combination of photopatch testing and
   computerized conformational analysis. Curr Pharm Des. 2008;14(27):2833-9.
   
   
10. Pigatto PD, Guzzi G, Schena D, Guarrera M, Foti C, Francalanci S, Cristaudo
    A, Ayala F, Vincenzi C. Photopatch tests: an Italian multicentre study from 2004
    to 2006. Contact Dermatitis. 2008 Aug;59(2):103-8

[ top ]

Ana Gimenéz-Arnau

[ top ]

Dr. Margarida Goncalo

1. Drug eruptions
   • The value of patch testing according to the drug and clinical pattern of DE
     
   • Pharmacogenetics in DE
     
   • In vitro activation of DC by skin sensitizers and drugs causing DE
2. Photosensitivity.
   • Contact photoallergens and systemic photosensitizers
3. Contact dermatitis
   • Perfume allergy
     
   • Hair dye allergy
     
   • Immediate reactions
     
   • Metal allergy in orthopaedic prosthesis intolerance
4. Chronic urticaria

1. A European multi-centre photopatch test study (EMCPTTS).
   Kerr AC, Ferguson J, Haylett AK, Rhodes LE, Adamski H, Alomar A, Serra E, Antoniou C, Aubin F, Vigan M, Biedermann T, Fischer J, Bourrains JL, Bruynzeel D, Rustemeyer T, Carrascosa JM, Chowdhury MM, de la Cuadra J, Foti C, Gardeazabal J, Gawkrodger DJ, Gimenez-Arnau A, Gonçalo M, Goossens A, Lecha M, Marguery MC, Neuman NJ, Niklassin B, Peyron JL, Pigatto P, Spiewak R, Stone N, Tanew A, Thomas P, Bonnevalle,A, Wilkinson SM, Wolf P, Gruber-Wackernagel A, Wulf HC
   Br J Dermatol 2012 Jan 27 doi:10.111/J.1365-2133.2012.10857.x
   
2. Patch testing in fixed drug eruptions. A 20 year review
   Pedro Andrade, A Brinca, M Gonçalo
   Contact Dermatitis. 2011: 65: 195-201. doi: 10.1111/j.1600-0536.2011.01946.x.
   
3. Value of patch tests in clindamycin-related drug eruptions
   Neide Pereira, MM Canelas, F Santiago, MM Brites, M Gonçalo
   Contact Dermatitis. 2011 Jun 20. doi: 10.1111/j.1600-0536.2011.01942.x
   
4. Signal transduction profile of chemical sensitisers in dendritic cells: An endpoint to be included in a cell-based in vitro alternative approach to hazard identification?
   Bruno Neves, M Gonçalo, A Figueiredo, CB Duarte, MC Lopes, MT Cruz
   Toxicol Appl Pharmacol. 2011 Jan 15;250(2):87-95. Epub 2010 Oct 13
   
5. Design and feasibility of an international study assessing the prevalence of contact allergy to fragrances in the general population: The European Dermato-Epidemiology Network Fragrance Study.
   Marta Rossi, P-J Coenraads, T Diepgen, Å Svensson, P Elsner, M Gonçalo, M Bruze, L Naldi
   Dermatology 2010 DOI: 10.1159/000319757 (published online 25 September)
   
6. Photoallergic contact dermatitis from benzydamine presenting mainly as lip dermatitis
   M Miguel Canelas, JC Cardoso, M Gonçalo, A Figueiredo
   Contact Dermatitis 2010: 63: 85-88
   
7. Allergic contact dermatitis to decylglucoside in Tinosorb M.
   Pedro Andrade, M Gonçalo, A Figueiredo
   Contact Dermatitis 2010: 62: 119-120
   
8. Epicutaneous patch testing in drug hypersensitivity syndrome (DRESS)
   Felicidade Santiago, M Gonçalo, R Vieira, S Coelho, A Figueiredo
   Contact Dermatitis 2010: 62: 47-53
   
9. Effect of lipopolysaccharide, skin sensitizers and irritants on thioredoxin-1 expression in dendritic cells: relevance of different signalling pathways
   Vera Francisco, BM Neves, MT Cruz, M Gonçalo, A Figueiredo, CB Duarte, MC Lopes
   Arch Dermatol Res 2010 May;302(4):271-82
   
10. Photopatch testing with an extended series of photoallergens. A 5- year study
    J Cardoso, MM Canelas, M Gonçalo, A Figueiredo
    Contact Dermatitis 2009: 60:325-329

[ top ]

Prof. An Goossens

• Different aspects of contact dermatitis to corticosteroids, such as cross sensitivity
  
• Contact dermatitis to cosmetics
  
• Occupational contact dermatitis (in cooperation with M. Bruze)
  
• Computer applications for practising dermatologists (Co 2)
  
  CODEX (pharmaceutical products)
  COSME (cosmetic products)
  INFAL (information on allergens and sensitization sources)
  CDREF (in cooperation with L. Conde Salazar, contact dermatitis literature references)
  EXPCA (expert program on P. C.)
  CFLDR (patient information)
  CDESK (combination of list functions of CODEX, COSME, CFLDR)
  PATCH (hierarchical search for allergens)
  

1. Isaksson M, Brandao FM, Bruze M, Goossens A.
   Recommendation to include budesonide and tixocortol pivalate in the European standard series. ESCD and EECDRG. European Society of Contact Dermatitis.
   Contact Dermatitis 2000; 43(1):41-42.
   Abstract
   
2. De Maeseneer M, Shahabpour M, Van Roy F, Goossens A, De Ridder F, Clarijs J et al.
   Mr imaging of the medial collateral ligament bursa: findings in patients and anatomic data derived from cadavers.
   AJR Am J Roentgenol 2001; 177(4):911-917.
   Abstract
   
3. Goossens A, Bedert R, Zimerson E.
   Allergic contact dermatitis caused by nickel and cobalt in green plastic shoes.
   Contact Dermatitis 2001; 45(3):172.
   Abstract
   
4. Huygens S, Barbaud A, Goossens A.
   Frequency and relevance of positive patch tests to cyclohexylthiophthalimide, a new rubber allergen.
   Eur J Dermatol 2001; 11(5):443-445.
   Abstract
   
5. De Paepe K, Hachem JP, Vanpee E, Goossens A, Germaux MA, Lachapelle JM et al.
   Beneficial effects of a skin tolerance-tested moisturizing cream on the barrier function in experimentally-elicited irritant and allergic contact dermatitis.
   Contact Dermatitis 2001; 44(6):337-343.
   Abstract
   

[ top ]

Christophe le Coz

• Textile dermatitis
  
• Occupational contct dermatitis
  
• Ketoprofen (photo)contact dermatitis and consequences
  
• Development of patch testing improvement
  

[ top ]

Prof. Jean-Pierre Lepoittevin

• Molecular immunotoxicology / Hapten-protein interaction studies based on the use of 13C labeled molecules and NMR.
  
• Development of in chemico alternative methods in immunotoxicology / Development of QSAR’s and peptide reactivity tests in the field of contact dermatitis.
  
• Development of new photoactivable derivatives interacting with DNA
  
• Molecular recognition: CMH – haptenized peptides – T-cell receptors
  

1. Gerberick GF, Troutman JA, Foertsch LM, Quijano M, Dobson RL, Goebel C, Lepoittevin JP. Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system.
   Toxicol Sci, 2009, 112, 164-174.
   
2. Lepoittevin JP, Berl V, Gimenez-Arnau E. Alpha-Methylene-Gamma-butyrolactones : versatile skin bioactive natural products.
   Chem Rec, 2009, 9, 258-270.
   
3. Kireche M, Giménez-Arnau E, Lepoittevin JP. Preservatives in cosmetics: reactivity of allergenic formaldehyde releasers toward amino acids through breakdown products other than formaldehyde.
   Contact Dermatitis, 2010, 63, 192-202.
   
4. Merckel F, Bernard G, Mutschler J, Giménez-Arnau E, Gerberick GF, Lepoittevin JP. Effect of a microemulsion system on hapten-peptide reactivity studies - Example of hydroxycitronellal and citral, fragrance skin sensitizer, with glutathione.
   Chem Res Toxicol, 2010, 23, 1433-41.
   
5. Bonefeld CM, Nielsen MM, Rubin IMC, Vennegaard MT, Dabelsteen S, Giménez-Arnau E, Lepoittevin JP, Geisler C, Johansen JD. Enhanced sensitization and elicitation responses by mixtures of common fragrance allergens.
   Contact Dermatitis, 2011, 65, 336-342.
   
6. Troutman JA, Foertsch LM, Kern PS, Dai J, Quijano J, Dobson RLM, Lepoittevin JP, Gerberick GF. Evaluation of lysine as an important nucleophile for screening skin sensitization.
   Toxicol Sci, 2011, 122, 422-36.
   
7. Kao D, Chaintreau A, Lepoittevin JP, Gimenez-Arnau A. Synthesis of sensitizing allylic hydroperoxides and EPR spin-trapping studies on the formation of radical in iron systems as potential initiators of the sensitizing pathway.
   J Org Chem, 2011, 76, 6188-6200.
   
8. Kireche M, Peiffer JL, Antonios D, Fabre I, Giménez-Arnau E, Pallardy M, Lepoittevin JP, Ourlin JC. Skin sensitization to bronopol, a formaldehyde-releaser: 2-bromoethanol and bromonitromethane as potential reactive degradation products.
   Chem Res Toxicol, 2011, 24, 2115-2128.
   
9. Thyssen JP, Gimenez-Arnau, Lepoittevin JP, Menné T, A Boman A, Schnuch A. The Critical Review of Methodologies and Approaches to Assess the Inherent Skin Sensitization Potential (skin allergies) of Chemicals.
   Contact Dermatitis, 2012, 66, 11-70.
   

[ top ]

Prof. Howard I. Maibach

• Effect of moisturizers on the skin
  
• Patterns of hand eczema (visual and instrumental examinations)
  
• Decontamination of chemicals from the skin
  
• Predictability - QSAR
  
• Percutaneous penetration
  
• Irritant dermatitis syndrome
  

1. Levin CY, Maibach HI.
   Do cool water or physiologic saline compresses enhance resolution of experimentally-induced irritant contact dermatitis?
   Contact Dermatitis 2001; 45(3):146-150.
   Abstract
   
2. Mallon J, Chu MT, Maibach HI.
   Occupational allergic contact dermatitis from methyl chloroform (1,1,1-trichloroethane)?
   Contact Dermatitis 2001; 45(2):107.
   Abstract
   
3. Jerschow E, Hostynek JJ, Maibach HI.
   Allergic contact dermatitis elicitation thresholds of potent allergens in humans.
   Food Chem Toxicol 2001; 39(11):1095-1108.
   Abstract
   
4. Singh J, Gross M, Sage B, Davis HT, Maibach HI.
   Regional variations in skin barrier function and cutaneous irritation due to iontophoresis in human subjects.
   Food Chem Toxicol 2001; 39(11):1079-1086.
   Abstract
   
5. Dannaker CJ, Maibach HI, Austin E.
   Allergic contact dermatitis to proparacaine with subsequent cross-sensitization to tetracaine from ophthalmic preparations.
   Am J Contact Dermat 2001; 12(3):177-179.
   Abstract
   

[ top ]

Thomas Rustemeyer

• Immunological mechanisms in allergic and irritant contact dermatitis
  
• Metal allergy
  
• Fragrance allergy
  
• Photo contact dermatitis
  
• Occupational skin diseases
  
• Development of novel eczema treatment strategies

1. Nagtegaal MJ, Pentinga SE, Kuik J, Kezic S, Rustemeyer T. The role of the skin
   irritation response in polysensitization to fragrances.
   Contact Dermatitis. 2012 Mar 22.
   
2. Kerr AC, Ferguson J, Haylett AK, Rhodes LE, Adamski H, Alomar A, Serra E, Antoniou C, Aubin F, Vigan M, Biedermann T, Fischer J, Bourrain JL, Bruynzeel D, Rustemeyer T, Carrascosa JM, Chowdhury MM, de la Cuadra J, Foti C, Gardeazabal J, Gawkrodger DJ, Gimenez-Arnau A, Goncalo M, Goossens A, Lecha M, Marguery MC, Neumann NJ, Niklasson B, Peyron JL, Pigatto P, Spiewak R, Stone N, Tanew A, Thomas P, Bonnevalle A, Wilkinson SM, Wolf P, Gruber-Wackernagel A, Wulf HC. A European Multi-centre Photopatch Test Study (EMCPPTS).
   Br J Dermatol. 2012 Jan 27.
   
3. Peiser M, Tralau T, Heidler J, Api AM, Arts JH, Basketter DA, English J, Diepgen TL, Fuhlbrigge RC, Gaspari AA, Johansen JD, Karlberg AT, Kimber I, Lepoittevin JP, Liebsch M, Maibach HI, Martin SF, Merk HF, Platzek T, Rustemeyer T, Schnuch A, Vandebriel RJ, White IR, Luch A. Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects. Current knowledge assembled at an international workshop at BfR, Germany.
   Cell Mol Life Sci. 2012 Mar;69(5):763-81.
   
4. van Gils RF, Boot CR, Knol DL, Rustemeyer T, van Mechelen W, van der Valk PG, Anema JR. The effectiveness of integrated care for patients with hand eczema: results of a randomized, controlled trial.
   Contact Dermatitis. 2012 Apr;66(4):197-204.
   
5. Muris J, Feilzer AJ, Rustemeyer T, Kleverlaan CJ. Palladium allergy prevalence is underestimated because of an inadequate test allergen.
   Contact Dermatitis. 2011 Jul;65(1):62
   
6. Franken SM, Genders RE, de Gruijl FR, Rustemeyer T, Pavel S. Skin hardening
   effect in patients with polymorphic light eruption: Comparison of UVB hardening
   in hospital with a novel home UV-hardening device.
   J Eur Acad Dermatol Venereol. 2011 Dec 6.
   
7. Martin SF, Esser PR, Schmucker S, Dietz L, Naisbitt DJ, Park BK, Vocanson M,
   Nicolas JF, Keller M, Pichler WJ, Peiser M, Luch A, Wanner R, Maggi E, Cavani A,
   Rustemeyer T, Richter A, Thierse HJ, Sallusto F. T-cell recognition of chemicals,
   protein allergens and drugs: towards the development of in vitro assays.
   Cell Mol Life Sci. 2010 Dec;67(24):4171-84.
   
8. Toebak MJ, Gibbs S, Bruynzeel DP, Scheper RJ, Rustemeyer T. Dendritic cells: biology of the skin.
   Contact Dermatitis. 2009 Jan;60(1):2-20.
   
9. Pentinga SE, Kuik DJ, Bruynzeel DP, Rustemeyer T. Do 'cinnamon-sensitive' patients react to cinnamate UV filters? Contact Dermatitis. 2009 Apr;60(4):210-3.
   dos Santos GG, Reinders J, Ouwehand K, Rustemeyer T, Scheper RJ, Gibbs S. Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound.
   Toxicol Appl Pharmacol. 2009 May 1;236(3):372-82.

[ top ]

Prof. Rik J. Scheper

• Multidrug resistance: mechanisms protecting cells against exogenous toxic substances
  
• Tumor immunology: development of dendritic cell-based vaccines, aiming at T cell-mediated immunity; (reversal of) immunological tolerance
  
• Contact allergy: same mechanistic approaches as previous project: e.g.
  - effect of allergens on Langerhans' cells migration
  - cross-reactivity studies (in vivo Guinea pig model, including retest model; in-vitro T-cell clonal approach)
  - cytokine studies, related to immunological tolerance, Th1, Th2, ... (Co 1, in collaboration with Peter Frosch)
  - retest model studies
  

1. Hensbergen PJ, van Der Raaij-Helmer EM, Dijkman R, Der Schors RC, Werner-Felmayer G, Boorsma DM et al.
   Processing of natural and recombinant CXCR3-targeting chemokines and implications for biological activity.
   Eur J Biochem 2001; 268(18):4992-4999.
   Abstract
   
2. van der Vliet HJ, von Blomberg BM, Nishi N, Reijm M, Voskuyl AE, van Bodegraven AA et al.
   Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage.
   Clin Immunol 2001; 100(2):144-148.
   Abstract
   
3. Siva AC, Raval-Fernandes S, Stephen AG, LaFemina MJ, Scheper RJ, Kickhoefer VA et al.
   Up-regulation of vaults may be necessary but not sufficient for multidrug resistance.
   Int J Cancer 2001; 92(2):195-202.
   Abstract
   
4. de Jong MC, Slootstra JW, Scheffer GL, Schroeijers AB, Puijk WC, Dinkelberg R et al.
   Peptide transport by the multidrug resistance protein MRP1.
   Cancer Res 2001; 61(6):2552-2557.
   Abstract
   
5. Schellens JH, Maliepaard M, Scheper RJ, Scheffer GL, Jonker JW, Smit JW et al.
   Transport of topoisomerase I inhibitors by the breast cancer resistance protein. Potential clinical implications.
   Ann N Y Acad Sci 2000; 922:188-194.
   Abstract
   

[ top ]

Dr. Ian R. White

• Regulatory aspects and consumer protection
  
• Type I reactions
  
• Preservative allergy
  
• Fragrances – allergens and allergy control
  
• Contact urticaria
  
• Clinical contact dermatitis
  
• Photopatch testing
  
• Hair dye allergen control
  

1. Fletcher CL, White IR.
   Type I hypersensitivity to latex and fungal alpha-amylase in a laboratory worker.
   Contact Dermatitis 2001; 45(3):165.
   Abstract
   
2. Basketter DA, Wright ZM, Warbrick EV, Dearman RJ, Kimber I, Ryan CA et al.
   Human potency predictions for aldehydes using the local lymph node assay.
   Contact Dermatitis 2001; 45(2):89-94.
   Abstract
   
3. McFadden JP, Ross JS, White IR, Basketter DA.
   Clinical allergy to cocamidopropyl betaine: reactivity to cocamidopropylamine and lack of reactivity to 3-dimethylaminopropylamine.
   Contact Dermatitis 2001; 45(2):72-74.
   Abstract
   
4. Wakelin SH, Smith H, White IR, Rycroft RJ, McFadden JP.
   A retrospective analysis of contact allergy to lanolin.
   Br J Dermatol 2001; 145(1):28-31.
   Abstract
   
5. Banerjee P, White IR.
   Allergic contact dermatitis at the application site of an electrosurgical earthing plate occurring in a windscreen repairer.
   Contact Dermatitis 2001; 44(2):97.
   Abstract
   

[ top ]